What's the study about?
The research team is studying breast tissue samples from women who have not had breast cancer, who have worked either day or night shifts for at least five consecutive years to better understand how wake/sleep cycle disruptions may increase breast cancer risk.
The research team has enrolled enough day-shift workers but still needs night-shift workers!
What's involved?
If you join the Shift Work and Breast Cancer Risk Study you will be contacted by phone to answer questions about your health and work history. If you are eligible for the study and decide to participate, you will be asked to complete a consent form and a questionnaire about your work history, your shift work, your sleep patterns, factors that contribute to stress in your life, your job satisfaction, family medical history, and additional background information. You will receive and return the materials in the mail (at no cost to you). After reviewing the completed questionnaires, the research team will choose the women who they will ask to provide the breast tissue samples.
To collect the tissue samples, the researchers and the Army of Women are collaborating with the Susan G. Komen for the Cure Tissue Bank at the Indiana University Simon Cancer Center in Indianapolis. If you are chosen to participate and you choose to provide a breast tissue sample, you will be asked to attend a tissue collection event at the Komen Tissue Bank on January 28 or 29, 2012, in Indianapolis, whichever is most convenient for you. In addition to donating tissue for this study, you will also be asked to donate tissue and a blood sample to be included in the Komen Tissue Bank for future studies not related to this specific study.
The Komen Tissue Bank obtains and stores specimens (tissue, blood, urine, or saliva) for researchers to use in their breast cancer studies. Just as the Army of Women serves as a resource for researchers looking for women, the Komen Tissue Bank is a resource for any researcher looking for healthy tissue sample. When you arrive at the Komen Tissue Bank, you will be asked to complete a separate Consent Form document and questionnaire for the Komen Tissue Bank.
A breast surgeon will perform approximately 4 core breast biopsies, removing cells from your breast with a needle under local anesthesia. This is an outpatient procedure and usually takes about 30 minutes. One of the tissue samples will be sent to Dr. Finkielstein for her analyses related to this study and the remaining samples will be stored at the Komen Tissue Bank. You will also be asked to donate a blood sample for the Komen Tissue Bank.
Please note: In order to participate in this study, you will need to agree to provide breast tissue samples that will be shared between this study and the Komen Tissue Bank. You can learn more about the Komen Tissue Bank click here or follow this link: https://komentissuebank.iu.edu
The researchers need to enroll approximately 23 more night-shift workers.
Who is conducting the study?
Carla Finkielstein, PhD, Virginia Polytechnic Institute and State University, Blacksburg, Virginia
Where?
IU Simon Cancer Center Komen Tissue Bank, Indianapolis, IN
Who can participate?
You can join the Shift Work and Breast Cancer Risk Study if you match ALL of these MAIN categories:
- You are a woman between 30-65 years old
- You have never been diagnosed with breast cancer (it is OK if you have a history of other cancers)
- You do not have the BRCA1 or BRCA2 mutation (if known; if you do not know, you can still participate in the study)
- You have worked night shifts for at least 5 consecutive years at some point in your life. Women who are/were "rotating night-shift workers" -- women who worked at least three nights per month, in addition to day and evening hours -- can also sign up.
- You are able to go to the Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center in Indianapolis, IN, on January 28 or 29, 2012, for the core biopsy procedure
- You have never had a breast reduction or breast implants
- You are NOT allergic to local anesthetics (numbing medicine)
- You are NOT receiving a therapeutic blood thinner (this does NOT include aspirin)
- You have NOT undergone a total abdominal hysterectomy (removal of the ovaries and uterus)
- You are NOT currently pregnant or were pregnant within the last 12 months
- You are NOT currently lactating or have lactated within the last 12 months
- You understand that if you are eligible and choose to join this study, you are agreeing to participate in both the Shift Work and Breast Cancer Risk Study AND the Komen Tissue Bank. Some of your tissue sample will be sent to Dr. Finkielstein and the rest will be stored at the Komen Tissue Bank.
Please note: If you have already submitted an RSVP for this study, you will not be able to RSVP again, as our system only allows ONE RSVP per study. If you think that you now qualify for this study, please email us directly at
studies@armyofwomen.org to let us know that you can't RSVP online and that you would like to sign up.
I sent this study info to some friends!
ReplyDeleteHi Annemarie, and all who come here.
ReplyDeleteThanks for sharing Army of Women's studies. I've read about women on night shifts having higher incidence of breast cancer with the theory being it's related to interrupted melatonin. Being under the lights all night rather than sleeping in the dark. There was a study where blind women had significantly lower rates of breast cancer also theorized to be tied to light and melatonin. Interesting ....
Rachel,
ReplyDeleteThank you for sharing that information. Idelle Davidson shared information about another study specific to melatonin levels that was conducted in Boston. Her comment is on yesterday's blog with the complete info (rather than cut and paste the whole thing!).
I am convinced as we continue to stick together, a more cohesive effort will be put forth and we will begin to see change. It's time to make noise and start sending more funds in different directions.
We have to start thinking out of the box... or, better yet, as my daughter profoundly says, "Box, WHAT box? Forget the box is even there." I'm down with that.
AnneMarie